Okay, time to think creatively about how we use computers. Some very bright people at NYU's Media Research Lab have come up with several proof-of-concept examples of Multi-touch interaction computing.
I recommend watching the video, then also catching Apple's much older Knowledge Navigator video. How might these sorts of interfaces affect the way we use computers for research, writing, teaching?
Addendum: for another take on GUIs, check out Lowfat, a prototype of some pretty fascinating software. See especially the video of it in action.